The burden of influenza B in Europe: a prospective multi-country strain surveillance study using community-based specimens

Duration: 2010 - 2011

Seasonal influenza in Humans is caused by influenza type A strains H1N1 and H3N2, strains of influenza B lineage B/Victoria and B/Yamagata.
It is known that in several seasonal influenza Epidemics there is a co- circulation of both sub-types of influenza A and both lineages of influenza B. Much attention has been paid to influenza in the last three decades, especially influenza A (H3N2) and, more recently, pandemic influenza A (H1N1). Many fewer studies have looked specifically at influenza B or comparisons between the influenza B and A.
The objective of the IBGP study is to describe influenza B cases by age and strain lineage, using outpatient data from European countries on clinical symptoms, duration of illness, complications, prescription, and absenteeism.
Study design: Multi-country observational descriptive study

All patients consulting a General Practitioner (GP) or a Paediatrician due to an ILI, during the influenza season 2010-2011 in the enrolled countries.

Cases: Patients presenting ILI who are lab-confirmed influenza B through the sentinel surveillance. Each country will collect all possible cases of influenza B according to the inclusion criteria and follow them up during a period of 28 days after swabbing.

Cohort comparison: Patients presenting ILI lab-negative for influenza B and similarly followed-up as cases.

Data collection: Standardised hard copy case report forms (CRF) developed according to the Protocol objectives.

D0: Time_0 day Standard lab form collected through the GP surveillance system with each specimen collected

D7: Time_7 days (± 2 days) Case-report form will be filled by GP or nurses through a telephone survey or a face to face contact

D28: Time_28 days (± 5 days) Standard questionnaire will be asked by telephone.
Scientific publications
Dit project wordt gesubsidieerd door
In dit project werken we samen met
Open Rome, Paris, France
Royal College of General Practitioners Research and Surveillance Centre, Birmingham, UK