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| Hoang, U., Button, E., Armstrong, M., Okusi, C., Ellis, J., Zambon, M., Anand, S., Delanerolle, G., Hobbs, R., Summeren, J. van, Paget, J., Lusignan, S. de. Assessing the clinical and socioeconomic burden of respiratory syncytial virus in children aged under 5 years in primary care: protocol for a prospective cohort study in England and report on the adaptations of the study to the COVID-19 pandemic. JMIR Research Protocols: 2022, 11(8), p. Art. e38026.

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| Dros, J.T., Bos, I., Bennis, F.C., Wiegersma, S., Paget, J., Seghieri, C., Barrio Cortés, J., Verheij, R.A. Detection of primary Sjögren’s syndrome in primary care: developing a classifcation model with the use of routine healthcare data and machine learning. BMC Primary Care: 2022, 23(1), p. Art. nr. 199.

… Background Primary Sjögren's Syndrome (pSS) is a rare autoimmune disease … develop an algorithm to identify possible pSS patients in primary care. We built a machine learning algorithm which was based …

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| Hempenius, M., Rijken, S., Groenwold, R.H.H., Hek, K., Boer, A. de, Klungel, O.H., Gerdarsdottir, H. Primary nonadherence to drugs prescribed by general practitioners: a Dutch database study. British Journal of Clinical Pharmacology: 2022, 89(1), p. 268-278.

… Aim Primary nonadherence (PNA) is defined as not filling the … prescription databases. This study aims to estimate PNA in primary care in the Netherlands and to investigate associated …

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| Groenewegen, P., Hansen, J., Fahy, N., Haarmann, A., Montante, S., Muscat, N.A., Poldrugovac, M., Ricciardi, W., Tomaselli, G. Priority setting and cross-country learning: the relevance of TO-REACH for primary care. Primary Health Care Research and Development

… Aim To inform the primary care community about priorities for research in primary care as came up from the European project TO-REACH …

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| Barbazza, E., Verheij, R.A., Ramerman, L., Klazinga, N., Kringos, D. Optimising the secondary use of primary care prescribing data to improve quality of care: a qualitative analysis. BMJ Open: 2022, 12(7), p. Art. e062349.

… and key considerations for optimising the actionability of primary care prescribing data to improve quality of care in the Dutch … (organisational) and macro (policy) contexts of the Dutch primary care system. Participants The study involved 28 …

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| Summeren, J. van, Meijer, A., Moleman, Y., Hendriksen, J., Korevaar, J., Wijsman, L., Goderski, G., Hooiveld, M., Paget, J. Disease burden of an RSV infection in young children in primary care in the Netherlands: period October 2020 – September 2021: results RSV ComNet II-study: the Netherlands. Utrecht: Nivel, 2022. 8 p.

… the disease burden of RSV infection in young children in primary care. - Data collection takes place in several European … the disease burden of RSV infection in young children in primary care. - Data collection takes place in several …

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| Tran, P.B., Kazibwe, J., Nikolaidis, G.F., Linnosmaa, I., Rijken, M., Olmen, J. van. Costs of multimorbidity: a systematic review and meta-analyses. BMC Medicine: 2022, 20(1), p. Art. nr. 234.

… costs of multimorbidity through addressing the following primary and secondary research questions: What evidence … costs, such as costs of hospitalization, outpatient care, emergency care, and drugs. Conclusions Multimorbidity … costs of multimorbidity through addressing the following primary and secondary research questions: What evidence …

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| Ramerman, L., Hek, K., Cramer-van der Welle, C., Simons-Winters, E., Middelweerd, A., Lambooij, A., Verheij, R. Incentivizing appropriate prescribing in primary care: development and first results of an electronic health record-based pay-for-performance scheme. Health Policy: 2022, 126(10), p.1010-1017.

… Part of the funding of Dutch General Practitioners (GPs) care is based on pay-for-performance, including an incentive … A., Verheij, R. Incentivizing appropriate prescribing in primary care: development and first results of an electronic … p.1010-1017. … Incentivizing appropriate prescribing in primary care: development and first results of an electronic …

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| Bagaria, J., Jansen, T., Marques, D.F., Hooiveld, M., McMenamin, J., Lusigman, S. de, Vilcu, A.M., Meijer, A., Rodrigues, A.P., Brytting, M., Mazagatos, C., Cogdale, J., Werf, S. van der, Dijkstra, F., Guiomar, R., Enkirch, T., Valenciano, M. Rapidly adapting primary care sentinel surveillance across seven countries in Europe for COVID-19 in the first half of 2020: strengths, challenges, and lessons learnt. Eurosurveillance: 2022, 27(26), p. Art. nr. 2100864.

… and aim As the COVID-19 pandemic began in early 2020, primary care influenza sentinel surveillance networks within the … collection. Strengths included established networks of primary care providers, highly qualified testing laboratories …

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| Deursen, B. van, Hooiveld, M., Marks, S., Snijdewind, I., Kerkhof, H. van den, Wintermans, B., Bom, B., Schimmer, B., Fanoy, E. Increasing incidence of reported scabies infestations in the Netherlands, 2011–2021. PLoS One: 2022, 17(6), p. Art. nr. e0268865.

… of scabies (per 1,000 persons) of persons consulting in primary care from 2011-2020. The other data source captured the … of scabies (per 1,000 persons) of persons consulting in primary care from 2011-2020. The other data source captured …

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| Dankers, M., Berk-Bulsink, M.J.E., Dalfsen-Slingerland, M. van, Nelissen-Vrancken, H.J.M.G., Mantel-Teeuwisse, A.K., Dijk, L. van. Non-adherence to guideline recommendations for insulins: a qualitative study amongst primary care practitioners. BMC Primary Care: 2022, 23, p. Art. nr. 150.

… This qualitative study aimed to identify the reasons why primary care healthcare professionals prescribe insulins that are not … in guidelines. Methods Digital focus groups with primary care practitioners were organised. A topic list was …

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| Liemburg, G.B., Korevaar, J.C., Zomeren, W.T.G. van, Berendsen, A.J., Brandenburg, D. Follow-up of curatively treated cancer in primary care: a qualitative study of the views of Dutch GPs. British Journal of General Practice: 2022, 72(721), p. e592-e600.

… Follow-up for cancer typically occurs in secondary care, and improved survival has increased demands on these … care for curatively treated patients from secondary to primary care (care substitution). Aim To explore the opinions … study of the opinions of purposively sampled GPs in Dutch primary care. Method Focus group sessions and individual …

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| Meekes, W.M.A., Leemrijse, C.J., Korevaar, J.C., Stanmore, E.K., Goor, L.I.A.M. van de. Implementing falls prevention in primary care: barriers and facilitators. Clinical Interventions in Aging: 2022, 17, p. 885-902.

… Purpose Limited information is available concerning primary care providers' encountered barriers and facilitators when … falls prevention and providing interventions in primary care. Development of a more successful implementation …

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| Kissling, E., Hooiveld, M., Martínez-Baz, I., Mazagatos, C., William, N., Vilcu, A.M., Kooijman, M.N., Ilić, M., Domegan, L., Machado, A., Lusignan, S. de, Lazar, M., Meijer, A., Brytting, M., Casado, I., Larrauri, A., Murray, J.L.K., Behillil, S., Gier, B. de, Mlinarić, I., O'Donnell, J., Rodrigues, A.P., Tsang, R., Timnea, O., Lange, M. de, Riess, M., Castilla, J., Pozo, F., Hamilton, M., Falchi, A., Knol, M.J., Kurečić Filipović, S., Dunford, L., Guiomar, R., Cogdale, J., Cherciu, C., Jansen, T., Enkirch, T., Basile, L., Connell, J., Gómez, V., Sandonis Martín, V., Bacci, S., Rose, A., Pastore Celentano, L., Valenciano, M. Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe: multicentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021. Eurosurveillance: 2022, 27(21), p. Art. nr. 2101104.

… Individuals with COVID-19 or acute respiratory symptoms at primary care/community level in 10 European countries were tested for SARS-CoV-2. We measured complete primary course overall VE by vaccine brand and by time since …

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| Ballering, A., olde Hartman, T., Verheij, R., Rosmalen, J. Sex and gender differences in help-seeking of patients with somatic symptoms. Journal of Psychosomatic Research: 2022, 157, p. 110823. Conference abstract held on 8 September 2021, held at start Nederlandse Vereniging Gender & Gezondheid (NVG&G), The Netherlands

… assess the independent associations of sex and gender with primary care help-seeking for somatic symptoms in the general Method … female sex rather than feminine gender associated with primary care help-seeking behaviour for somatic symptoms. …

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| Ramerman, L., Rijpkema, C., Bos, N., Flinterman, L.E., Verheij, R.A. The use of out-of-hours primary care during the first year of the COVID-19 pandemic. BMC Health Services Research: 2022, 22(2), p. Art. nr. 679.

… professional for most health problems. Out-of-hours (OOH) primary care is provided by regional OOH services. Changes in … investigated how the COVID-19 pandemic changed the use of primary care OOH services during the first year of the …

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| Groenewegen, P., Dirkzwager, A., Dam, A. van, Massalimova, D., Sirdifield, C. The health of detainees and the role of primary care: position paper of the European Forum for Primary Care. Primary Health Care Research and Development: 2022, 23(e29)

… Aim This position paper aims to increase awareness among primary care practitioners and policymakers about the specific and … incarceration. Methods We focus on the importance of primary care and of continuity of care between prison and …

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| Groenewegen, P.P., Spreeuwenberg, P., Siriwardena, A.N., Sirdifield, C., Willems, S. Migrant GPs and patients: a cross-sectional study of practice characteristics, patient experiences and migration concordance. Scandinavian Journal of Primary Health Care: 2022, 40(2), p. 181-189.

… and patients on experiences of patients in key areas of primary care quality and discrimination. Design and setting Secondary … patient survey data from QUALICOPC (Quality and Costs of Primary Care), a cross-sectional study of GPs and their …

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| Knottnerus, B., Heijmans, M., Rademakers, J. The role of primary care in informing and supporting people with limited health literacy in the Netherlands during the COVID-19 pandemic: a qualitative interview study. BMC Primary Care: 2022, 23(1), p. Art. nr. 115.

… we aimed to make recommendations on the possible role of primary care in informing and supporting patients with limited HL … applies in particular to patients with chronic illnesses. Primary care professionals are in the ideal position to take …

Publication

| Summeren, J. van. Management of childhood functional constipation in primary care Groningen: RUG, 2022. 169 p. Proefschrift van de Rijksuniversiteit Groningen

… aged 4-17 years, with functional constipation (FC) in primary care. Therefore, we have performed the BOKi pragmatic … J. van. Management of childhood functional constipation in primary care Groningen: RUG, 2022. 169 p. Proefschrift van de …

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| Herter, W.E., Khuc, J., Cinà, G., Knottnerus, B., Numans, M.E., Wiewel, M.A., Bonten, T.N., Bruin, D.P. de, Esch, T. van, Chavannes, N.H., Verheij, R.A. Impact of a machine learning–based decision support system for urinary tract infections: prospective observational study in 36 primary care practices. JMIR Medical Informatics: 2022, 10(5), p. Art. nr. e27795.

… and obstacles that positively impact the quality of health care practice with ML. Methods The CDSS was developed by … was needed. In this prospective observational study, 36 primary care practices used the software for 4 months. … performed using electronic health records from the Nivel Primary Care Database. Patients for whom the software was …

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| Heins, M.J., Ligt, K.M. de, Verloop, J., Siesling, S., Korevaar, J.C. Opportunities and obstacles in linking large health care registries: the primary secondary cancer care registry - breast cancer. BMC Medical Research Methodology: 2022, 22(1), p. Art. nr. 124.

… how we dealt with these challenges when creating the Primary Secondary Cancer Care Registry (PSCCR)- Breast Cancer. Methods The PSCCR - … patients (NCR), and 2) consultations and diagnoses from primary care electronic health records of about 10% of Dutch …

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| Wiersema, C., Oude Voshaar, R.C., Brink, R.H.S. van den, Wouters, H., Verhaak, P., Comijs, H.C., Jeuring, H.W. Determinants and consequences of polypharmacy in patients with a depressive disorder in later life. Acta Psychiatrica Scandinavica: 2022, 146(1), p. 85-97.

… often congregate in the geriatric population. The primary objective is to identify determinants of polypharmacy … burden requires physicians to prescribe medications with care. … Objectives Polypharmacy and late-life depression … often congregate in the geriatric population. The primary objective is to identify determinants of polypharmacy …

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| Batenburg, R., Kroezen, M. Education and planning: anticipating and responding to skill gaps, changing skill needs and competencies. In: C.Maier, M. Kroezen, R. Busse & M. Wismar, (Eds.). Skill-mix Innovation, Effectiveness and Implementation Improving Primary and Chronic Care. New York: Cambridge University Press. Series: European observatory on health systems and policies p. 294-320.

… Innovation, Effectiveness and Implementation Improving Primary and Chronic Care. New York: Cambridge University Press. Series: European … Innovation, Effectiveness and Implementation Improving Primary and Chronic Care. New York: Cambridge University …

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| Wezel, N. van, Heide, I. van der, Devillé, W.L.J.M., Blom, M.M., Hoopman, R., Francke, A.L. Knowledge about dementia among family caregivers with a Turkish or Moroccan immigrant background: development and validation of a Dementia Knowledge Scale. Journal of Primary Care and Community Health: 2022, 13, p. 1-9.

… those with a higher level; those who frequently provided care versus those who did so less frequently; and those who … those with a higher level; those who frequently provided care versus those who did so less frequently; and those who … and validation of a Dementia Knowledge Scale. Journal of Primary Care and Community Health : 2022, 13, p. 1-9. … …

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| Winkelmann, J., Williams, G.A., Rijken, M., Polin, K., Maier, C.B. Chronic conditions and multimorbidity: skill-mix innovations for enhanced quality and coordination of care. In: Maier, B., Kroezen, M., Busse, R., Wismar, M. Skill-mix Innovation, Effectiveness and Implementation: Improving Primary and Chronic Care. Cambridge University Press, 2022. p. 152-220.

… Innovation, Effectiveness and Implementation: Improving Primary and Chronic Care. Cambridge University Press, 2022. … The prevalence of … Innovation, Effectiveness and Implementation: Improving Primary and Chronic Care. Cambridge University Press, 2022. …

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| Batenburg, R., Kroezen, M. Education and planning: anticipating and responding to skill gaps, changing skill needs and competencies. New York: Camebridge University Press, 2022.

… Innovation, Effectiveness and Implementation Improving Primary and Chronic Care. New York: Cambridge University Press … Most European … countries are faced with a chain of challenges in health care. Due to the ageing of the population and a growing …

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| Hek, K., Boogaerts, T., Verheij, R.A., Loof, H. de, Dijk, L. van, Nuijs, A.L.N. van, Meijer, W.M., Philips, H. Opioid prescribing in out-of-hours primary care in Flanders and the Netherlands: a retrospective cross-sectional study PLoS One: 2022, 17(4), p. Art. e0265283.

… the risks. Acute and chronic pain is often treated in a primary care out-of-hours (OOH) setting. This setting may be a driver … to investigate weak and strong opioid prescribing at OOH primary care services (PCS) in Flanders (Northern, …

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| Azizi, B., Tilburgs, B., Hout, H.P.J. van, Heide, I. van der, Verheij, R.A., Achterberg, W.P., Steen, J.T. van der, Joling, K.J. Occurrence and timing of advance care planning in persons with dementia in general practice: analysis of linked electronic health records and administrative data. Frontiers in Public Health: 2022, 10, p. Art. nr. 653174.

… Background Advance care planning (ACP) is a process of communication in which … records coded with the International Classification of Primary Care. Socio-demographic characteristics were derived … records coded with the International Classification of Primary Care. Socio-demographic characteristics were derived …

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| Hek, K., Rolfes, L., Puijenbroek, E. van, Flinterman, L., Vorstenbosch, S., Dijk, L. van, Verheij, R. Electronic health record-triggered research infrastructure combining real-world electronic health record data and patient-reported outcomes to detect benefits, risks, and impact of medication: development study. JMIR Medical Informatics: 2022, 10(3), p. Art. nr. e33250.

… general practice EHR data that are sent to the Dutch Nivel Primary Care Database weekly. Patients with OAB were flagged weekly … infrastructure was developed and implemented. In the Nivel Primary Care Database, 2933 patients with OAB from 27 general …