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| Vervloet, M., Weesie, Y., Kocks, J., Dijk, L. van, Korevaar, J. Asthma medication in Dutch primary care: asthma medication use and its relation with asthma outcomes. Utrecht: Nivel, 2020. 54 p.

… into the medication use of patients with asthma in Dutch primary care. It also provides insight into the relationship between … for Asthma). We used data derived from the Nivel Primary Care Database, which includes routine care data …

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| Heins, M.J., Hooiveld, M., Korevaar, J.C. Vaccine Coverage Dutch National Influenza Prevention Program 2019: brief monitor. Utrecht: Nivel, 2020. 3 p.

… data from general practitioners participating in the Nivel Primary Care Database to monitor the vaccine coverage of the Dutch … data from general practitioners participating in the Nivel Primary Care Database to monitor the vaccine coverage of the …

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| Maass, S.W.M.C., Boerman, L.M., Brandenbarg, D., Verhaak, P.F.M., Maduro, J.H., Bock, G.H. de, Berendsen, A.J. Symptoms in long-term breast cancer survivors: a cross-sectional study in primary care. The Breast: 2020, 54, p. 133-138.

… diagnosis and 350 women without cancer matched by age and primary care physician. All women completed a questionnaire enquiring … Scale. Cardiovascular diseases were diagnosed from primary care records. In a multivariable logistic regression …

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| Hek, K., Esch, T.E.M. van, Lambooij, A., Weesie, Y.M., Dijk, L. van. Guideline adherence in antibiotic prescribing to patients with respiratory diseases in primary care: prevalence and practice variation. Antibiotics: 2020, 9(9), p. Art. nr. 571.

… account for a large part of antibiotic prescriptions in primary care. However, guidelines advise restrictive antibiotic … account for a large part of antibiotic prescriptions in primary care. However, guidelines advise restrictive …

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| Stol, D.M. Cost-effectiveness of selective cardiometabolic disease prevention in primary care. Utrecht: Nivel, 2020. 193 p. Proefschrift van de Universiteit Utrecht

… drug treatment. Improvement of CMD risk assessment in primary care by early identification of patients at high-risk might … to provide a framework for selective CMD prevention in primary care. This program is directed at all patients aged …

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| Badenbroek, I.F. Evaluation of a stepwise prevention program for cardiometabolic diseases in primary care. Utrecht: Nivel, 2020. 183 p. Proefschrift van de Universiteit Utrecht

… and reach of selective CMD prevention program in primary care, by assessing the contribution of patient and practice … and reach of selective CMD prevention program in primary care, by assessing the contribution of patient and …

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| Mens, K. van, Elzinga, E., Nielen, M., Lokkerbol, J., Poortvliet, R., Donker, G., Heins, M., Korevaar, J., Dückers, M., Aussems, C., Helbich, M., Tiemens, B., Gilissen, R., Beekman, A., Beurs, D. de. Applying machine learning on health record data from general practitioners to predict suicidality. Internet Interventions: 2020, 21(100337)

… to support GPs recognizing suicidal behaviour in primary care patients using routinely collected general practice … study used data from a national representative primary care database including over 1.5 million patients …

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| Groenewegen, P.P., Bosmans, M.W.G., Boerma, W.G.W., Spreeuwenberg, P. The primary care workforce in Europe: a cross-sectional international comparison of rural and urban areas and changes between 1993 and 2011. European Journal of Public Health: 2020, 30(Suppl. 4), p. iv12-iv17.

… Rural areas have problems in attracting and retaining primary care workforce. This might have consequences for the existing … Rural areas have problems in attracting and retaining primary care workforce. This might have consequences for the …

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| Jansen, T., Hek, K., Schellevis, F.G., Kunst, A.E., Verheij, R.A. Socioeconomic inequalities in out-of-hours primary care use: an electronic health records linkage study. European Journal of Public Health: 2020, 30(6), p. 1049-1055.

… (SEP) is related to higher healthcare use in out-of-hours primary care services (OPCSs). We aimed to determine whether … 988 040 patients in 2017 (251 DGPs, 27 OPCSs) from Nivel Primary Care Database were linked to sociodemographic data …

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| Woestenberg, P.J., Guevara Morel, A.E., Boogaards, J.A., Hooiveld, M., Schurink-van 't Klooster, T.M., Hoebe, C.J.P.A., Sande, M.A.B. van der, Benthem, B.H.B. van. Partial protective effect of bivalent human papillomavirus 16/18 vaccination against anogenital warts in a large cohort of dutch primary care patients. Clinical Infectious Diseases: 2020, p. 7 p..

… on AGWs. Methods We linked general practice (ie, primary care) data from women born between 1993 and 2002, who had … on AGWs. Methods We linked general practice (ie, primary care) data from women born between 1993 and 2002, who …

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| Beers-Tas, M. van, Nielen, M.M.J., Twisk, J.W.R., Korevaar, J., Schaardenburg, D. van. Increased primary care use for musculoskeletal symptoms, infections and comorbidities in the years before the diagnosis of inflammatory arthritis. RMD Open: 2020, 6(2), p. 9 p..

… diagnosis of IA, using the International Classification of Primary Care coding system. Cases were 2314 adults with a new … 2012 and 2016; controls were matched 1:2. The frequency of primary care visits was compared using logistic regression. …

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| Meijer, L.J., Groot, E. de, Honing-de Lange, G., Kearney, G., Schellevis, F.G., Damoiseaux, R.A.M.J. Transcending boundaries for collaborative patient care.: , 2021. p. 27-31.

… and medical specialists (MSs) create collaborative patient care agreements (CPCAs) to improve intraprofessional … to identify contradictions between the activity systems of primary and secondary care that could result in expansive … to identify contradictions between the activity systems of primary and secondary care that could result in expansive …

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| Maghroudi, E., Hooijdonk, C.M.J. van, Dijk, L. van, Boland, G., Haas, C. de, Journée-Gilissen, M., Velden, J. van der, Vervloet, M., Westerhof, H., Rademakers, J.J.D.J.M., Borgsteede, S.D. Development of comprehensible prescription label instructions: a study protocol for a mixed-methods approach. Frontiers in Pharmacology: 2020

… health literacy skills, and to implement improvements in primary health care. Methods We used a mixed-methods approach, which … health literacy skills, and to implement improvements in primary health care. Methods We used a mixed-methods …

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| Scaioli, G., Schäfer, W.L.A., Boerma, W.G.W., Spreeuwenberg, P.M.M., Schellevis, F., Groenewegen, P.P. Communication between general practitioners and medical specialists in the referral process: a Cross-sectional survey in 34 countries. BMC Family Practice: 2020, 21(54), p. 9 p..

… is important in order to avoid fragmentation of care thus achieving a higher quality of care and ensuring … referral process is associated with the organisation of primary care within a country, the characteristics of the GPs, and the characteristics of the primary care practices themselves. Methods An analysis of a …

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| Asten, L. van, Pinzon, A.L., Kassteele, J. van de, Donker, G., Lange, D.W. de, Dongelmans, D.A., Keizer, N.F. de, Hoek, W. van der. The association between influenza infections in primary care and intensive care admissions for severe acute respiratory infection (SARI): a modelling approach. Influenza and Other Respiratory Viruses: 2020, p. 12 p..

… of influenza circulation we studied how influenza in primary care relates to intensive care unit (ICU) admissions using a … associated with medically attended influenza infections in primary care; b) how this varies by season; c) the time lag …

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| Kooijman, M.K., Buining, E.M., Swinkels, I.C.S., Koes, B.W., Veenhof, C. Do therapist effects determine outcome in patients with shoulder pain in a primary care physiotherapy setting? Physiotherapy: 2020, 107, p. 111-117.

… outcome. Design Observational cohort study. Setting Primary care physiotherapy practices. Participants Data on patients … between 2009 and 2012 were derived from the NIVEL Primary Care Database. Personality traits of the …

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| Stol, D.M., Hollander, M., Damman, O., Nielen, M.M.J., Badenbroek, I.F., Schellevis, F.G., Wit, N.J. de. Mismatch between self-perceived and calculated cardiometabolic disease risk among participants in a prevention program for cardiometabolic disease: a cross-sectional study. BMC Public Health: 2020, 20(1), p. Art. nr. 740.

… data from a randomized controlled trial conducted in a primary care setting. Seven thousand five hundred forty-seven … data from a randomized controlled trial conducted in a primary care setting. Seven thousand five hundred forty-seven …

Publication

| Weesie, Y.M., Hek, K., Schermer, T.R.J., Schellevis, F.G., Leufkens, H.G.M., Rook, E.J., Dijk, L. van. Use of opioids increases with age in older adults: an observational study (2005–2017). Frontiers in Pharmacology: 2020, 11(648), p. 8 p..

… and duration of opioid prescribing to older adults, in primary care and to explore differences between older patients from different ages. Methods Primary care data (2005–2017) were derived from routine …

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| Verkissen, M.N., Penders, W.H., Onwuteaka-Philipsen, B.D., Moreels, S., Donker, G.A., Vega Alonso, T., Block, L. van den, Deliens, L. End-of-life communication in advanced cancer: international trends (2009–2014). BMJ Supportive & Palliative Care: 2022, 12(e2), p. e236 - e247.

… in their practice and reported for five end-of-life care topics whether they had been discussed with the patient. … to new roles in communication for healthcare providers in primary and secondary care. Improved information sharing … to new roles in communication for healthcare providers in primary and secondary care. Improved information sharing …

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| Badenbroek, I.F., Nielen, M.M.J., Hollander, M., Stol, D.M., Drijkoningen, A.E., Kraaijenhagen, R.A., Wit, N.J. de, Schellevis, F.G. Mapping non-response in a prevention program for cardiometabolic diseases in primary care: How to improve participation? Preventive Medicine Reports: 2020, 19, p. Art. nr. 101092.

… prevention programs for cardiometabolic diseases (CMD) in primary care is often overlooked. The aim for this study was to define factors that influence the primary response to a selective CMD prevention program and to …

Publication

| Melchiorre, M.G., Papa, R., Quattrini, S., Lamura, G., Barbarella, F. Integrated Care Programs for People with Multimorbidity in European Countries: eHealth Adoption in Health Systems. BioMed Research International: 2020, p. Art. nr. 9025326.

… applications have the potential to provide new integrated care services to patients with multimorbidity (MM), also … health model (financing system), overall strength of primary care (PC) (structure/service delivery process), and … health model (financing system), overall strength of primary care (PC) (structure/service delivery process), and …

Publication

| Pati, S., Pati, S., Akker, M. van den, Schellevis, F.F.G., Jena, S., Burgers, J.S. Impact of comorbidity on health-related quality of life among type 2 diabetic patients in primary care. Primary Health Care Research and Development: 2020, p. Art. nr. e9.

… associated with complications, comorbidities, and lifelong care. Objectives The present study aims to explore the impact … of HRQL among type 2 diabetic patients attending primary care. Methods A total of 912 type 2 diabetic patients attending primary care centers in India were assessed using a …

Publication

| Flinterman, L.E., Kuiper, J.G., Korevaar, J.C., Dijk, L. van, Hek, K., Houben, E., Herings, R., Franken, A.A.M., Graaf, J.P. de, Horikx, A., Janssens, M., Meijer, R., Wijbenga, A., Puijenbroek, E. van, Wolffenbuttel, B.H.R., Links, T.P., Bisschop, P.H., Fliers, E. Impact of a forced dose-equivalent levothyroxine brand switch on plasma TSH: a cohort study. Thyroid: 2020, 30(6), p. 821-828.

… Background Patients with primary hypothyroidism are treated with levothyroxine in … prescription and laboratory test data: the Nivel Primary Care Database and the PHARMO database network. …

Publication

| Kooijman, M.K., Swinkels, I.C.S., Koes, B.W., Bakker, D. de, Veenhof, C. One in six physiotherapy practices in primary care offer musculoskeletal ultrasound - an explorative survey BMC Health Services Research: 2020, 20, p. Art. nr. 246.

… of physiotherapists with musculoskeletal ultrasound in a primary care setting with patients presenting with shoulder … complaints. Methods A random sample of 1000 owners of primary care physiotherapy practices was sent a questionnaire …

Publication

| Rose, A., Kissling, E., Emborg, H.D., Larrauri, A., McMenamin, J., Pozo, F., Trebbien, R., Mazagatos, C., Whitaker, H., Valenciano, M., Hooiveld, M. Interim 2019/20 influenza vaccine effectiveness: six European studies( Sep 2019 - Janu 2020). Eurosurveillance: 2020, 25(10)

… from six European studies, covering 10 countries and both primary care and hospital settings. Methods All studies used the … for all ages were 29% to 61% against any influenza in the primary care setting and 35% to 60% in hospitalised older …

Publication

| Seijmonsbergen-Schermers, A.E., Zondag, D.C., Nieuwenhuize, M., Akker, T. van den, Verhoeven, C.J., Geerts, C.C., Schellevis, F.G., Jonge, A. de. Regional variations in childbirth interventions and their correlations with adverse outcomes, birthplace and care provider: a nationwide explorative study. PLoS One: 2020, 15(3), p. Art. nr. e0229488.

… characteristics using multivariable logistic regression. Primary outcomes were intrapartum referral, birthplace, and interventions used in midwife- and obstetrician-led care. Correlations both between primary outcomes and between adverse outcomes were calculated …

Publication

| Reukers, D.F.M., Marbus, S.D., Smit, H., Schneeberger, P., Donker, G., Hoek, W. van der, Gageldonk-Lafeber, A.B. van. Media reports as a source for monitoring impact of influenza on hospital care: qualitative content analysis. JMIR Public Health and Surveillance: 2020, 6(1), p. Art. nr. e14627.

… countries, has a robust influenza surveillance system in primary care. However, there is a lack of real-time nationally … countries, has a robust influenza surveillance system in primary care. However, there is a lack of real-time …

Publication

| Huis in het Veld, J.G., Willemse, B.M., Asch, I.F.M. van, Groot Zwaaftink, R.B.M., Verkade, P.J., Twisk, J.W.R., Verkaik, R., Blom, M.M., Meijel, B. van, Francke, A.L. Online self-management support for family caregivers dealing with behavior changes in relatives with dementia (part 2): randomized controlled trial. Journal of Medical Internet Research: 2020, 22(2), p. 12 p..

… minor intervention consisting of only the e-bulletins. The primary outcome was family caregivers’ self-efficacy in … minor intervention consisting of only the e-bulletins. The primary outcome was family caregivers’ self-efficacy in …

Publication

| Mitratza, M., Kunst, A.E., Harteloh, P.P.M., Nielen, M.M.J., Klijs, B. Prevalence of diabetes mellitus at the end of life: An investigation using individually linked cause-of-death and medical register data. Diabetes Research and Clinical Practice: 2020, 160, p. Art. nr. 108003.

… mellitus at the end of life is associated with complex care, its end-of-life prevalence is uncertain. Our aim is to … of deaths in the Netherlands (2015-2016) included in Nivel Primary Care Database (Nivel-PCD; N = 18,162). The proportion … estimate the most (19.7%-points). Of the cases added by primary care data, 76.3% had a severe or intermediate status. …

Publication

| Monge, S., Duijster, J., Kommer, G.J., Kassteele, J. van de, Donker, G.A., Krafft, T., Engelen, P., Valk, J.P., Waard, J. de, Nooij, J. de, Hoek, W. van der, Asten, L. van. Use of ambulance dispatch calls for surveillance of severe acute respiratory infections. Emerging Infectious Diseases: 2020, 26(1), p. 148-150.

… syndromes reflect incidence of influenza-like illness in primary care. Associations are highest in children (15%–34% of … syndromes reflect incidence of influenza-like illness in primary care. Associations are highest in children (15%–34% …