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The effectiveness and cost-effectiveness of an integrated cardiometabolic risk assessment and treatment program in primary care (the INTEGRATE study).
Stol, D., Badenbroek, I., Hollander, M., Nielen, M., Schellevis, F., Wit, N. de. The effectiveness and cost-effectiveness of an integrated cardiometabolic risk assessment and treatment program in primary care (the INTEGRATE study).: , 2014.
The effectiveness and cost-effectiveness of an integrated cardiometabolic risk assessment and treatment program in primary care (the INTEGRATE study): a stepped-wedge randomized controlled trial protocol. Rationale: The increasing prevalence of cardiometabolic disease (CMD), including cardiovascular disease, diabetes mellitus and chronic kidney disease, in combination with an ageing population is a major public health problem. Early detection and management of individuals at risk for CMD is urgent in order to prevent future health problems and further increase in health care costs. General practice is the optimal setting for identifying and treating patients at risk. Prevention programs for identifying and treating patients with an increased risk for CMD have been proven feasible, however the effectiveness and cost-effectiveness of prevention programs for CMD need to be established first to justify broad implementation in primary care. Therefore, in the INTEGRATE study, a “Personalized Prevention Approach for Cardio-Metabolic Risk” (PPA CMR), a primary prevention program with an incorporated tailored lifestyle intervention, is tested. The objective of the INTEGRATE study is to investigate the effectiveness and cost-effectiveness of PPA CMR. Methods In this stepped-wedge randomized controlled trial (starting
March 2014), all patients aged 45-70 years listed in 40 general practices without CMD will be invited to participate in PPA CMR. After an online risk estimation, patients with a score above threshold will visit their GP for additional measurements, followed by tailored treatment with medication and/or lifestyle counseling. After one year of follow-up, differences in risk profile and incidence of CMD will be used to determine the effectiveness and cost- effectiveness of PPA CMR. Conclusion & Clinical Relevance: The INTEGRATE study provides insight into the effectiveness and cost-effectiveness of PPA CMR. This is essential information for further large-scale implementation of primary prevention programs for CMD and other health care prevention programs. (aut. ref.)
March 2014), all patients aged 45-70 years listed in 40 general practices without CMD will be invited to participate in PPA CMR. After an online risk estimation, patients with a score above threshold will visit their GP for additional measurements, followed by tailored treatment with medication and/or lifestyle counseling. After one year of follow-up, differences in risk profile and incidence of CMD will be used to determine the effectiveness and cost- effectiveness of PPA CMR. Conclusion & Clinical Relevance: The INTEGRATE study provides insight into the effectiveness and cost-effectiveness of PPA CMR. This is essential information for further large-scale implementation of primary prevention programs for CMD and other health care prevention programs. (aut. ref.)
The effectiveness and cost-effectiveness of an integrated cardiometabolic risk assessment and treatment program in primary care (the INTEGRATE study): a stepped-wedge randomized controlled trial protocol. Rationale: The increasing prevalence of cardiometabolic disease (CMD), including cardiovascular disease, diabetes mellitus and chronic kidney disease, in combination with an ageing population is a major public health problem. Early detection and management of individuals at risk for CMD is urgent in order to prevent future health problems and further increase in health care costs. General practice is the optimal setting for identifying and treating patients at risk. Prevention programs for identifying and treating patients with an increased risk for CMD have been proven feasible, however the effectiveness and cost-effectiveness of prevention programs for CMD need to be established first to justify broad implementation in primary care. Therefore, in the INTEGRATE study, a “Personalized Prevention Approach for Cardio-Metabolic Risk” (PPA CMR), a primary prevention program with an incorporated tailored lifestyle intervention, is tested. The objective of the INTEGRATE study is to investigate the effectiveness and cost-effectiveness of PPA CMR. Methods In this stepped-wedge randomized controlled trial (starting
March 2014), all patients aged 45-70 years listed in 40 general practices without CMD will be invited to participate in PPA CMR. After an online risk estimation, patients with a score above threshold will visit their GP for additional measurements, followed by tailored treatment with medication and/or lifestyle counseling. After one year of follow-up, differences in risk profile and incidence of CMD will be used to determine the effectiveness and cost- effectiveness of PPA CMR. Conclusion & Clinical Relevance: The INTEGRATE study provides insight into the effectiveness and cost-effectiveness of PPA CMR. This is essential information for further large-scale implementation of primary prevention programs for CMD and other health care prevention programs. (aut. ref.)
March 2014), all patients aged 45-70 years listed in 40 general practices without CMD will be invited to participate in PPA CMR. After an online risk estimation, patients with a score above threshold will visit their GP for additional measurements, followed by tailored treatment with medication and/or lifestyle counseling. After one year of follow-up, differences in risk profile and incidence of CMD will be used to determine the effectiveness and cost- effectiveness of PPA CMR. Conclusion & Clinical Relevance: The INTEGRATE study provides insight into the effectiveness and cost-effectiveness of PPA CMR. This is essential information for further large-scale implementation of primary prevention programs for CMD and other health care prevention programs. (aut. ref.)