Publicatie

Publication date

Respiratory syncytial virus (RSV) associated primary care incidence estimates in adults aged 50 years and older in the Netherlands; 2016-2019.

Laarman, C., Vanhommerig, J., Summeren, J. van, Hooiveld, M., Meijer, A., Teirlinck, A., Stelma, F. Respiratory syncytial virus (RSV) associated primary care incidence estimates in adults aged 50 years and older in the Netherlands; 2016-2019. Utrecht: Nivel, 2024. 16 p.

Download the PDF
The aim of this study was to estimate the seasonal incidence rate of adults aged 50 years and older, who consulted their general practitioner (GP) with an RSV infection in the Netherlands. Medically attended RSV incidence rates were calculated by counting the weekly number of acute respiratory infection (ARI) disease episodes recorded by the GP in the electronic health records (EHR) and multiplying this number with the weekly proportion of specimens, with a laboratory-confirmed positive test result for RSV, collected via the national virological sentinel surveillance in primary care. To estimate the total number of adults that consulted the GP with RSV infection in the Netherlands, seasonal RSV infection incidence rate estimates were extrapolated to the Dutch population aged 50 years and older.

The incidence rate of adults aged 50 years and older who contacted their GP with an RSV infection was estimated to be 13.3 (95% confidence interval, CI: 9.8-17.6), 8.3 (95% CI: 6.0-11.2) and 9.3 (95% CI: 6.6-12.7) per 1,000 registered persons in general practice for the respiratory seasons 2016/2017, 2017/2018 and 2018/2019, respectively. RSV incidence rates were estimated to be higher in adults aged 75 years and older, compared to adults aged 50-74 years. Sub-group analyses were conducted to estimate RSV-associated incidence rates for patients groups that are considered to be at increased risk for medically attended RSV infection (e.g., chronic pulmonary disease). The medically attended RSV incidence rates for persons with chronic pulmonary disease were estimated to be higher compared to the total population of adults aged 50 years and older, or patients with e.g. diabetes mellitus or cardiac disease. The estimated total number of adults aged 50 years and older who contacted their GP with a RSV infection were estimated to be 89,100 (95% CI 66,100-118,100), 56,600 (95% CI 41,100-76,200), and 64,000 (95% CI 45,800-87,500) for the respiratory seasons 2016/2017, 2017/2018 and 2018/2019, respectively. These estimates on RSV infection among adults in primary care will help policymakers in making decisions on the implementation of new preventive measures.
Gegevensverzameling