Combined use of aspirin and proton pump inhibitors: a study in a Dutch general practice database, 2011-2012

Duration: Dec 2011 - Sep 2012

Background
People who have experienced a cardiovascular event often receive low-dose aspirin (LDASA). Because these agents can cause gastrointestinal complications, some of these patients are indicated for a proton pump inhibitor (PPI).

Aim
This study aims to provide insight into:
1. the extent of the combined use of LDASA with PPIs;
2. whether this combination is prescribed according to the latest evidence-based advice;
3. what the adherence to LDASA whether combined with PPIs or not is.

Method
The study uses data from the National Information Network for Family Medicine (LINH). Since 2001, LINH has been collecting data on disease supply and treatment in general practice. Within LINH, GP prescribing can be tracked over time.

Result
The study contributes to knowledge about the use of medication in people with an increased risk of cardiovascular disease. This insight can contribute to further optimization of (pharmaco)therapy for this group.