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Comorbidity and functioning in elderly (potential) rehabilitation patients with osteoarthritis of hip or knee: results from the CARPA-study.
Dijk, G.M. van, Veenhof, C., Dekker, J. Comorbidity and functioning in elderly (potential) rehabilitation patients with osteoarthritis of hip or knee: results from the CARPA-study. Annals of the Rheumatic Diseases: 2006, 65(suppl. 2) 408. Abstract. Annual European Congress of Rheumatology on 21-24 june 2006 in Amsterdam, the Netherlands.
Objective: Osteoarthritis is one of the most common diseases in older people. It also is one of the diseases with the highest rate of comorbidity. Only few studies have concentrated on comorbidity in OA. These studies vary with regard to study population, prevalence of comorbidity and comorbidity measures. There is evidence for an association between comorbidity and functioning. But studies are scarce. The objectives of this study are to describe the prevalence of comorbidity in elderly patients with knee or hip OA and to address the relationship between comorbidity and disability. Methods: A prospective cohort study was conducted in which 288 patients with hip or knee OA were followed up to 3 years. For these analyses, baseline measurements were used. Apart from demographic and clinical data, information about comorbidity (CIRS) and functioning (WOMAC, VAS, SF36, timed walking test) was collected by questionnaires and tests. Results: Preliminary analyses, including descriptive statistics and multivariate regression techniques, showed that the majority of the patients suffered comorbidity. The most prevalent conditions were cardiac diseases, diseases of eye, throat, nose and ear, urogenital diseases and endocrine or metabolic diseases. On average, patients suffered 5.3 diseases (including OA) with a mean severity of 1.7 (range 0-4). Morbidity count, i.e. having more diseases was associated with a decline in physical functioning on the WOMAC. It was also associated with lesser functional performance on the timed walking test and more pain on the VAS in specific groups of patients. A higher mean severity was associated with a decline in physical functioning on all functional outcome measures (including pain). There also seems to be a relation between the presence of specific comorbidities and functioning. Conclusion: In all, there is evidence for the importance of comorbidity in osteoarthritis of hip and knee. Furthermore, there are indications for an association between comorbidity and a decline in functioning. (aut. ref.)
Objective: Osteoarthritis is one of the most common diseases in older people. It also is one of the diseases with the highest rate of comorbidity. Only few studies have concentrated on comorbidity in OA. These studies vary with regard to study population, prevalence of comorbidity and comorbidity measures. There is evidence for an association between comorbidity and functioning. But studies are scarce. The objectives of this study are to describe the prevalence of comorbidity in elderly patients with knee or hip OA and to address the relationship between comorbidity and disability. Methods: A prospective cohort study was conducted in which 288 patients with hip or knee OA were followed up to 3 years. For these analyses, baseline measurements were used. Apart from demographic and clinical data, information about comorbidity (CIRS) and functioning (WOMAC, VAS, SF36, timed walking test) was collected by questionnaires and tests. Results: Preliminary analyses, including descriptive statistics and multivariate regression techniques, showed that the majority of the patients suffered comorbidity. The most prevalent conditions were cardiac diseases, diseases of eye, throat, nose and ear, urogenital diseases and endocrine or metabolic diseases. On average, patients suffered 5.3 diseases (including OA) with a mean severity of 1.7 (range 0-4). Morbidity count, i.e. having more diseases was associated with a decline in physical functioning on the WOMAC. It was also associated with lesser functional performance on the timed walking test and more pain on the VAS in specific groups of patients. A higher mean severity was associated with a decline in physical functioning on all functional outcome measures (including pain). There also seems to be a relation between the presence of specific comorbidities and functioning. Conclusion: In all, there is evidence for the importance of comorbidity in osteoarthritis of hip and knee. Furthermore, there are indications for an association between comorbidity and a decline in functioning. (aut. ref.)