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Effectiveness of exercise therapy in patients with osteoarthritis of the hip or knee.

Baar, M.E. van, Assendelft, W.J.J., Dekker, J., Oostendorp, R.A.B., Bijlsma, J.W.J. Effectiveness of exercise therapy in patients with osteoarthritis of the hip or knee. Arthritis and Rheumatism: 1999, 42(7), 1361-1369
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Objectives: To review the effectiveness of exercise therapy in patients with osteoarthritis (OA) of the hip of knee. Methods: A computerized literature search of Medline, Embase, and Cinahl was carried out. Randomized clinical trials on exercise therapy for OA of the hip of knee were selected if treatment had been randomly allocated and if pain , self-reported disability, observed diasbility, or patient's global assessment of effect had been used as outcome measures. The validity oftrials was systematically assessed by independent reviewers. Effect sizes and power estimates were calculated. A best evidence synthesis was conducted, weighting the studies with respect to their validity and power. Results: Six of the 11 assessed trials satisfied at least 50% of the validity criteria. Two trials had sufficient power to detect medium-sized effects. Effects sizes indicated small-to-moderate beneficial effects of exercise therapy on pain, small beneficial effects on both disability outcome measures, and moderate-to-great beneficial effects according to patient's global assessment of effect. Conclusions: There is evidence of beneficial effects of exercise therapy in patients with OA of the hip or knee. However, the small number of good studies restricts drawing firm conclusions. (aut.ref.)